HOSOKAWA ALPINE Aktiengesellschaft(细川阿尔派股份公司)商标

Pharmaceutical Industry


Generic or patented medicines are available in many dosage forms, e.g. as tablets or powders. However, the increasingly exacting product quality, safety and cost-efficiency requirements are common to them all. In order to meet these requirements, the pharmaceutical industry requires products with increasingly higher fineness levels.

Our company is a global leader in the comminution of pharmaceutical products. We develop versatile and efficient process solutions for reducing the size of pharmaceutical products. Thanks to many years of experience, our engineers excel in the development of both standard and specialised solutions. This benefits our product range and our customers’ processes with higher output rates and fitness for the future.

Safety and reliability across the entire process chain

In addition to guaranteeing reliable processes, Hosokawa Alpine provides all systems with maximum safety standards. Lines can be operated safely in every environment and at all times. Depending on the risk potential of the product, they are equipped with integrated WIP / CIP solutions even for high containment technologies. Our solutions are a class of their own: we deliver the complete system, from isolator right through to the process equipment and automation from one source. With our complete solutions, incompatibilities and interface problems are a thing of the past. All pharmaceutical lines comply with the strictest of international standards:

  • Monoblock components guarantee a minimum of weld lines and seals and a design that is free of deadlegs
  • A wide variety of surface roughness levels to suit any requirement
  • Encapsulated bearings with lifetime lubrication
  • Seals and filters with FDA-compliant materials
  • Special Pharmaplex® bearing concept provides clear separation of drive and process
  • Patented Pharmaplex® bearing concept ensures fully CIP/SIP-capable machines
  • Qualification documents and automation systems according to GAMP5

Case Study: all-rounder for highly active substances

Process solutions for highly active substances are often costly and require further investment into suitable operating facilities such as cleanrooms. At the same time, there is a rising demand for versatile solutions thatallow the production of different products and fineness levels without compromising the safety of the operators.

The solution: In response to these requirements, we have developed a unique concept: the multi-mill isolator. This system is highly versatile, yet compact and has potential for future applications because it combines several milling modules in one single system. The financial benefit: one isolator accommodates all processes – the customer saves a large proportion of the investment costs.


Pharma & Lab Division
Tel. +49 821 5906-283
Fax: +49 821 5906-620
»  e-mail

Hosokawa Alpine Compaction
– a Division of Hosokawa Alpine AG
Liebigstr. 8/2
74211 Leingarten, Germany
Tel: +49 7131 898669-221
»  e-mail

PDF Downloads:

  • Pharmaceutical Technology - GMP
    + 其它语言
  • Powder and Particle Processing for the Pharmaceutical Industry
  • High Containment
    + 其它语言
  • Multi Purpose Crusher MPC 150
    + 其它语言
  • Pharmapaktor C80-20
    + 其它语言
  • Cell culture media
  • Respiratory Drugs
  • Solid Pre-Crushers
    + 其它语言


我们在多个网页上为您提供包含详细信息的相应的产品宣传册。除此之外您还可以在我们 2 个业务部的统一下载产品宣传册汇总中找到所有的产品宣传册。 借助产品宣传册心愿单您可以将不同网页上的产品宣传册逐个收集起来,然后再进行下载。为此,您需要在一张表格中登记您的电子邮箱地址和一些其它信息。 我们会发给您一封电子邮件用于下载:邮件中包含的超链接可启动 PDF 产品宣传册文件下载。

PDF 心愿单:

您最新的心愿单: 0


我们在多个网页上为您提供包含详细信息的相应的产品宣传册。除此之外您还可以在我们 2 个业务部的统一下载产品宣传册汇总中找到所有的产品宣传册。 借助产品宣传册心愿单您可以将不同网页上的产品宣传册逐个收集起来,然后再进行下载。为此,您需要在一张表格中登记您的电子邮箱地址和一些其它信息。 我们会发给您一封电子邮件用于下载:邮件中包含的超链接可启动 PDF 产品宣传册文件下载。